Bai Lab

Spatial biology of cancer and aging

Lab Culture

We are committed to conducting open, rigorous, and exciting science, driven by curiosity and a focus on addressing the most important questions. Our work is deeply collaborative, grounded in mutual respect and shared purpose. We also strive to foster an inclusive and welcoming environment where all individuals—regardless of background—feel valued, supported, and empowered to contribute!

Principal Investigator

Zhiliang Bai, Ph.D.

Zhiliang is an Assistant Professor in the Department of Biological Engineering and an intramural member of the Koch Institute for Integrative Cancer Research at MIT. He obtained a B.E. in Measuring and Control Technology in 2015 and a Ph.D. in Instrument Science and Technology in 2021, both from Tianjin University. As a visiting graduate student in Dr. Rong Fan’s laboratory at Yale University, he developed microfluidic devices for active single-cell sequencing and established single-cell pipelines to characterize CAR T cells. He subsequently continued as a postdoctoral scholar in the same lab, co-advised by Dr. Mina Xu in Yale Pathology, where he investigated the mechanistic basis of durable cancer immunotherapy and led the development of multiple spatial omics technologies. His lab integrates spatial multi-omics innovation with RNA biology, digital pathology, and AI to advance cancer and aging research.

Position

2026-                Assistant Professor, Department of Biological Engineering, MIT

2026-                Intramural Member, Koch Institute for Integrative Cancer Research at MIT

2021-2025        Postdoc Associate, Department of Biomedical Engineering, Yale University

Honors and Awards

2025                 Arthur and Sandra Irving Cancer Immunology Young Scientists

2025                 Society for Immunotherapy of Cancer (SITC) Sparkathon Class of 2025 Emerging Leaders

2024                 Federation of Clinical Immunology Societies (FOCIS) Clinical Immunology Award

2024                 Tom and Joan Steitz RNA Fellow 

2023                 American Society of Hematology (ASH) Abstract Achievement Award

2023                 SITC Young Investigator Award

2023                 Biomedical Engineering Society (BMES)-CMBE Postdoc Researcher Award

2021                 Outstanding Graduate of Tianjin University

2020                 Shenghua Ye Scholarship in Instrument Science and Technology (10 nationwide)

2018                 National “Person of the Year” Nominee for Chinese University Students (30 nationwide)

2017                 Kechang Wang Scholarship (10 nationwide, ranking 1st)

2017                 Ten-Best Exceptional Students of Tianjin University & Presidential Scholarship (Ranking 1st)

2017                 National Scholarship of China

2016                 Committee of 100 Leadership Scholarship

Lab Members

Coming soon